DDIAS Antibody

Datasheet

Citations (1)

Code	CSB-PA006130
Size	US$119
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Image	Western Blot analysis of 823 293T AD293 Hela HepG2 cells using NOXIN Polyclonal Antibody
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Product Details
Citations
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q8IXT1

Target Names

DDIAS

Alternative Names

Chromosome 11 open reading frame 82 antibody; DNA damage induced apoptosis suppressor antibody; DNA damage induced apoptosis suppressor protein antibody; FLJ13936 antibody; FLJ25416 antibody; FLJ38838 antibody; Nitric oxide inducible gene protein antibody; Nitric oxide-inducible gene protein antibody; Noxin antibody; NOXIN_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of Human NOXIN.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:10000

Protocols

Western Blotting(WB) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

DNA Damage-Induced Apoptosis Suppressor Triggers Progression and Stemness of Glioma by Enhancing Lymphoid Enhancer-Binding Factor 1 Expression YL Chen,World journal of oncology,2024

Customer Reviews and Q&A

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Target Background

Function

May be an anti-apoptotic protein involved in DNA repair or cell survival.

Gene References into Functions

these findings indicate that the stability of the DDIAS protein is regulated by CHIP/HSP70-mediated proteasomal degradation and that CHIP overexpression stimulates the apoptosis of lung cancer cells in response to DNA-damaging agents PMID: 28079882
Noxin facilitated the expression of Cyclin D1 and Cyclin E1 through activating P38-activating transcription factor 2 signaling pathway, thus enhanced cell growth of breast cancer PMID: 28618963
EGF activates the ERK5/MEF2 pathway, which in turn induces DDIAS expression to promote cancer cell invasion by activating beta-catenin target genes PMID: 27412911
DDIAS is a target of NFATc1 and is associated with cisplatin resistance in lung cancer cells. PMID: 26493727
NOXIN overexpression, as a result of genomic DNA gain or amplification, promotes HCC tumorigenesis by accelerating DNA synthesis and cell cycle progression, where NOXIN functions as a cofactor of DNA polymerase-primase complex PMID: 25612832

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Subcellular Location

Cytoplasm. Nucleus.

Tissue Specificity

Highly expressed in colorectal and lung cancer tissues.

Database Links

HGNC: 26351

KEGG: hsa:220042

STRING: 9606.ENSP00000414687

UniGene: Hs.165607

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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