DHRS9 Antibody

Datasheet

Code	CSB-PA006867DA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA006867DA01HU at dilution of 1:100 Immunofluorescent analysis of A549 cells using CSB-PA006867DA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) DHRS9 Polyclonal antibody

Uniprot No.

Q9BPW9

Target Names

DHRS9

Alternative Names

3 alpha hydroxysteroid dehydrogenase antibody; 3-@alpha-HSD antibody; 3-@alpha-hydroxysteroid dehydrogenase antibody; 3-alpha hydroxysteroid dehydrogenase antibody; 3-alpha-HSD antibody; 3alpha HSD antibody; Dehydrogenase/reductase SDR family member 9 antibody; DHRS9 antibody; DHRS9_HUMAN antibody; NADP dependent retinol dehydrogenase/reductase antibody; NADP-dependent retinol dehydrogenase/reductase antibody; RDH-E2 antibody; Rdh15 antibody; RDHE2 antibody; RDHL antibody; RDHTBE antibody; retinol dehydrogenase homolog antibody; Retinol dehydrogenase; tracheobronchiol epithelail cell-specific antibody; RETSDR8 antibody; SDR family; member 9 antibody; SDR9C4 antibody; short chain dehydrogenase/reductase family 9 antibody; short chain dehydrogenase/reductase family 9C; member 4 antibody; Short chain dehydrogenase/reductase retSDR8 antibody; Short-chain dehydrogenase/reductase retSDR8 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Dehydrogenase/reductase SDR family member 9 protein (23-319AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The DHRS9 Antibody (Product code: CSB-PA006867DA01HU) is Non-conjugated. For DHRS9 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA006867DB01HU	DHRS9 Antibody, HRP conjugated	ELISA
FITC	CSB-PA006867DC01HU	DHRS9 Antibody, FITC conjugated
Biotin	CSB-PA006867DD01HU	DHRS9 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. Plays also a role in the biosynthesis of retinoic acid from retinaldehyde. Can utilize both NADH and NADPH.

Gene References into Functions

The study findings suggest that DHRS9 might be a useful diagnostic and prognostic marker for oral squamous cell carcinoma PMID: 30149992
DHRS9 is a specific and stable marker of human regulatory macrophages. PMID: 28594751
decreased expression of DHRS9 correlates with tumor progression and may serve as a potential prognostic biomarker in colorectal cancer PMID: 26254099
Even at early stages of malignant transformation, a significant decrease in ADH1B, ADH3, RDHL, and RALDH1 mRNA levels was observed in 82, 79, 73, and 64% of tumor specimens, respectively PMID: 27239845
Dehydrogenase/reductase SDR family member 9 is a moonlighting protein that functions as both a metabolic enzyme and as a transcriptional repressor. PMID: 16691198
expression of retinol dehydrogenase L is regulated by APC and CDX2 PMID: 15190067
retinoic acid-responsive genes are induced by Epstein-Barr virus lytic infection through induction of a retinol-metabolizing enzyme, DHRS9 PMID: 17244623

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Subcellular Location

Microsome membrane. Endoplasmic reticulum membrane. Note=Associated with microsomal membranes.

Protein Families

Short-chain dehydrogenases/reductases (SDR) family

Tissue Specificity

Highly expressed in trachea and epidermis. Detected at lower levels in spinal cord, bone marrow, brain, tongue, esophagus, heart, colon, testis, placenta, lung, skeletal muscle and lymph node.

Database Links

HGNC: 16888

OMIM: 612131

KEGG: hsa:10170

STRING: 9606.ENSP00000316670

UniGene: Hs.179608

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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