DLGAP3 Antibody

Code CSB-PA006942GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
DLGAP3
Alternative Names
DLGAP3 antibody; DAP3Disks large-associated protein 3 antibody; DAP-3 antibody; PSD-95/SAP90-binding protein 3 antibody; SAP90/PSD-95-associated protein 3 antibody; SAPAP3 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human DLGAP3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
0.1M NaHCO3,0.1M Glycine, 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
Gene References into Functions
  1. several rare variants of the DLGAP3 gene were found in this study which may be associated with schizophrenia. PMID: 23414653
  2. This study provides suggestive evidence that DLGAP3 and its interactive effect with SLC1A1 might be involved in susceptibility to developing OC symptoms in schizophrenia patients receiving AAP treatment. PMID: 21990008
  3. This study generated preliminary evidence to link SAPAP3 variants to the development of earlier onset obsessive-compulsive disorder. PMID: 21295225
  4. DLGAP3 remains a promising candidate gene for Tourette Syndrome. PMID: 21184590
  5. Sapap3 is a promising functional candidate gene for human grooming disorder (obsessive compulsive disorder). PMID: 19051237
  6. Multiple rare SAPAP3 missense variants in trichotillomania and OCD. PMID: 19096451

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Subcellular Location
Cell membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic density. Cell junction, synapse.
Protein Families
SAPAP family
Database Links

HGNC: 30368

OMIM: 611413

KEGG: hsa:58512

STRING: 9606.ENSP00000235180

UniGene: Hs.733945

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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