DMRT3 Antibody, HRP conjugated

Code CSB-PA885692LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DMRT3 Polyclonal antibody
Uniprot No.
Target Names
DMRT3
Alternative Names
DMRT3 antibody; DMRTA3Doublesex- and mab-3-related transcription factor 3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Doublesex- and mab-3-related transcription factor 3 protein (92-224AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling limb movements. May regulate transcription during sexual development.
Gene References into Functions
  1. Thus, the deletion of the cis-regulatory element for DMRT3 in humans may cause impaired development of the forebrain and gait abnormalities, resulting in spastic CP. In conclusion, this study provides new mechanistic insights into the genetic basis of CP. PMID: 29305858
  2. Chromosome 9p loss is the hallmark of squamous cell carcinoma, and DMRT1, DMRT3 and DOCK8 genes at 9p24.3 might be of interest for the study of the pathophysiology of SCC as potential targets for therapeutic measures. PMID: 20596660
Subcellular Location
Nucleus.
Protein Families
DMRT family
Tissue Specificity
Expressed in testis.
Database Links

HGNC: 13909

OMIM: 614754

KEGG: hsa:58524

UniGene: Hs.189174

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