DMRT3 Antibody

Code CSB-PA885692LA01HU
Size US$166
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Image
  • IHC image of CSB-PA885692LA01HU diluted at 1:700 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DMRT3 Polyclonal antibody
Uniprot No.
Target Names
DMRT3
Alternative Names
DMRT3 antibody; DMRTA3Doublesex- and mab-3-related transcription factor 3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Doublesex- and mab-3-related transcription factor 3 protein (92-224AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The DMRT3 Antibody (Product code: CSB-PA885692LA01HU) is Non-conjugated. For DMRT3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA885692LB01HU DMRT3 Antibody, HRP conjugated ELISA
FITC CSB-PA885692LC01HU DMRT3 Antibody, FITC conjugated
Biotin CSB-PA885692LD01HU DMRT3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:500-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling limb movements. May regulate transcription during sexual development.
Gene References into Functions
  1. Thus, the deletion of the cis-regulatory element for DMRT3 in humans may cause impaired development of the forebrain and gait abnormalities, resulting in spastic CP. In conclusion, this study provides new mechanistic insights into the genetic basis of CP. PMID: 29305858
  2. Chromosome 9p loss is the hallmark of squamous cell carcinoma, and DMRT1, DMRT3 and DOCK8 genes at 9p24.3 might be of interest for the study of the pathophysiology of SCC as potential targets for therapeutic measures. PMID: 20596660
Subcellular Location
Nucleus.
Protein Families
DMRT family
Tissue Specificity
Expressed in testis.
Database Links

HGNC: 13909

OMIM: 614754

KEGG: hsa:58524

UniGene: Hs.189174

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