DNAJB4 Antibody

1. These new observations support the idea that HLJ1 is a tumor suppressor candidate and potential biomarker for breast cancer PMID: 28481734
2. HLJ1 is an endogenous Src inhibitor that can suppress cancer metastasis through complex interacting mechanisms. PMID: 27065329
3. HLJ1 is a strong tumor suppressor for colorectal carcinoma PMID: 24696714
4. Low expression of DNAJB4 is associated with gastric carcinomas. PMID: 24293545
5. Silencing of HLJ1 partially reverses the inhibition of cancer-cell invasion by andrographolide. PMID: 23306212
6. HBV could promote HLJ1 expression by up-regulating the transcription factor YY1. PMID: 21345358
7. acidic stress increases the association between HLJ1 and beta-actin to modulate migration of human lung cancer cells PMID: 20615403
8. HLJ1 switches the role of NPM1, which can act as tumor suppressor or oncogene, by modulating the oligomerization of NPM1 via HLJ1-NPM1 heterodimer formation and recruiting AP-2alpha to the MMP-2 promoter. PMID: 20145123
9. Results indicate that DjA1 and DjB4 of subfamilies A and B of human Hsp40 have different quaternary structures and chaperone functions. PMID: 15661747
10. The increase in HLJ1 and E-cadherin expression, as well as the suppression of invasion ability, can be reversed specifically by HLJ1 siRNA. PMID: 15782117
11. HLJ1 is a novel tumor suppressor in NSCLC, and high HLJ1 expression is associated with reduced cancer recurrence and prolonged survival of NSCLC patients. PMID: 16788156
12. Results show that curcumin induces HLJ1, through activation of the JNK/JunD pathway, and inhibits lung cancer cell invasion and metastasis by modulating E-cadherin expression. PMID: 18794131

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HGNC: 14886

OMIM: 611327

KEGG: hsa:11080

STRING: 9606.ENSP00000359799

UniGene: Hs.13852