DRG2 Antibody

Code CSB-PA007186LA01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DRG2 Polyclonal antibody
Uniprot No.
Target Names
DRG2
Alternative Names
Developmentally regulated GTP binding protein 2 antibody; Developmentally-regulated GTP-binding protein 2 antibody; DRG 2 antibody; DRG-2 antibody; drg2 antibody; DRG2_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Developmentally-regulated GTP-binding protein 2 protein (1-364AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The DRG2 Antibody (Product code: CSB-PA007186LA01HU) is Non-conjugated. For DRG2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA007186LB01HU DRG2 Antibody, HRP conjugated ELISA
FITC CSB-PA007186LC01HU DRG2 Antibody, FITC conjugated
Biotin CSB-PA007186LD01HU DRG2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation.
Gene References into Functions
  1. Taken together, our data demonstrate that DRG2 acts as a regulator of mitochondrial fission by controlling the expression of Drp1. PMID: 28363867
  2. Authors observed that knockdown of DRG2 in HeLa cells affected growth in a wound-healing assay, and tumorigenicity in nude mice xenografts. PMID: 27669826
  3. Results demonstrate that DRG2 is an endosomal protein and a key regulator of Rab5 deactivation and Tfn recycling. PMID: 26582392
  4. miR19153p functions as a silencer of apoptosis, which regulates lung cancer apoptosis via targeting DRG2/PBX2. PMID: 26572100
  5. Basal expression level of DRG2 is regulated by the Sp1 transcription factor. PMID: 21296692
  6. overexpression of DRG2 in Jurkat cells affects genes regulating cell-cycle arrest and apoptosis, and that these molecular changes may be important in the growth or differentiation of cells PMID: 15113831

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Subcellular Location
Nucleus. Cytoplasm.
Protein Families
TRAFAC class OBG-HflX-like GTPase superfamily, OBG GTPase family
Tissue Specificity
Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes.
Database Links

HGNC: 3030

OMIM: 602986

KEGG: hsa:1819

STRING: 9606.ENSP00000225729

UniGene: Hs.78582

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