DRG2 Antibody

Datasheet

Code	CSB-PA007186LA01HU
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) DRG2 Polyclonal antibody

Uniprot No.

P55039

Target Names

DRG2

Alternative Names

Developmentally regulated GTP binding protein 2 antibody; Developmentally-regulated GTP-binding protein 2 antibody; DRG 2 antibody; DRG-2 antibody; drg2 antibody; DRG2_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Developmentally-regulated GTP-binding protein 2 protein (1-364AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The DRG2 Antibody (Product code: CSB-PA007186LA01HU) is Non-conjugated. For DRG2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA007186LB01HU	DRG2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA007186LC01HU	DRG2 Antibody, FITC conjugated
Biotin	CSB-PA007186LD01HU	DRG2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation.

Gene References into Functions

Taken together, our data demonstrate that DRG2 acts as a regulator of mitochondrial fission by controlling the expression of Drp1. PMID: 28363867
Authors observed that knockdown of DRG2 in HeLa cells affected growth in a wound-healing assay, and tumorigenicity in nude mice xenografts. PMID: 27669826
Results demonstrate that DRG2 is an endosomal protein and a key regulator of Rab5 deactivation and Tfn recycling. PMID: 26582392
miR19153p functions as a silencer of apoptosis, which regulates lung cancer apoptosis via targeting DRG2/PBX2. PMID: 26572100
Basal expression level of DRG2 is regulated by the Sp1 transcription factor. PMID: 21296692
overexpression of DRG2 in Jurkat cells affects genes regulating cell-cycle arrest and apoptosis, and that these molecular changes may be important in the growth or differentiation of cells PMID: 15113831

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Subcellular Location

Nucleus. Cytoplasm.

Protein Families

TRAFAC class OBG-HflX-like GTPase superfamily, OBG GTPase family

Tissue Specificity

Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes.

Database Links

HGNC: 3030

OMIM: 602986

KEGG: hsa:1819

STRING: 9606.ENSP00000225729

UniGene: Hs.78582

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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