DTX3 Antibody, FITC conjugated

Datasheet
Code CSB-PA839833LC01HU
Size US$299
Uniprot No. Q8N9I9
Protocols ELISA Protocol
Immunogen Recombinant Human Probable E3 ubiquitin-protein ligase DTX3 protein (90-347AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Antigen Affinity Purified
Isotype IgG
Clonality Polyclonal
Alias Probable E3 ubiquitin-protein ligase DTX3 (EC 2.3.2.27) (Protein deltex-3) (Deltex3) (RING finger protein 154) (RING-type E3 ubiquitin transferase DTX3), DTX3, RNF154
Immunogen Species Homo sapiens (Human)
Research Area Epigenetics and Nuclear Signaling
Target Names DTX3
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Subcellular Location Cytoplasm
Protein Families Deltex family
Database Links

HGNC: 24457

OMIM: 613142

KEGG: hsa:196403

STRING: 9606.ENSP00000338050

UniGene: Hs.32374

Pathway Notch signaling pathway

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