DTX3 Antibody

Datasheet
Code CSB-PA699630
Size US$299
Uniprot No. Q8N9I9
Image
  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human lymphoma tissue, Primary antibody: CSB-PA699630(DTX3 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
Immunogen Fusion protein of Human DTX3
Raised in Rabbit
Species Reactivity Human,Mouse
Tested Applications ELISA,WB;ELISA:1:1000-1:2000,WB:1:200-1:1000
Relevance DTX3 functions as an E3 ubiquitin ligase. Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context By similarity. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Form Liquid
Conjugate Non-conjugated
Storage Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method Antigen affinity purification
Isotype IgG
Alias Deltex homolog 3 (Drosophila)
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Target Names DTX3
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Subcellular Location Cytoplasm
Protein Families Deltex family
Database Links

HGNC: 24457

OMIM: 613142

KEGG: hsa:196403

STRING: 9606.ENSP00000338050

UniGene: Hs.32374

Pathway Notch signaling pathway

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