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EARS2 Antibody, Biotin conjugated

Datasheet
Code CSB-PA705509LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) EARS2 Polyclonal antibody
Uniprot No.
Q5JPH6
Target Names
EARS2
Alternative Names
3230401I01Rik antibody; AL024049 antibody; COXPD12 antibody; EARS 2 antibody; ears2 antibody; GluRS antibody; Glutamate--tRNA ligase antibody; Glutamyl tRNA synthetase 2 mitochondrial antibody; KIAA1970 antibody; mitochondrial antibody; mKIAA1970 antibody; MSE1 antibody; Probable glutamyl tRNA synthetase; mitochondrial antibody; Probable glutamyl-tRNA synthetase antibody; RGD1307904 antibody; SYEM_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Probable glutamate--tRNA ligase, mitochondrial protein (42-166AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
Gene References into Functions
  1. This study presented that a new neurological disease, early-onset leukoencephalopathy with thalamus and brainstem involvement and high lactate, defined by a peculiar biphasic clinical course and caused by mutations in a single gene, EARS2. PMID: 22492562
Involvement in disease
Combined oxidative phosphorylation deficiency 12 (COXPD12)
Subcellular Location
Mitochondrion matrix.
Protein Families
Class-I aminoacyl-tRNA synthetase family, Glutamate--tRNA ligase type 1 subfamily
Database Links

HGNC: 29419

OMIM: 612799

KEGG: hsa:124454

STRING: 9606.ENSP00000343488

UniGene: Hs.620541

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