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EARS2 Antibody, Biotin conjugated

Datasheet
Code CSB-PA705509LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) EARS2 Polyclonal antibody
Uniprot No.
Q5JPH6
Target Names
EARS2
Alternative Names
3230401I01Rik antibody; AL024049 antibody; COXPD12 antibody; EARS 2 antibody; ears2 antibody; GluRS antibody; Glutamate--tRNA ligase antibody; Glutamyl tRNA synthetase 2 mitochondrial antibody; KIAA1970 antibody; mitochondrial antibody; mKIAA1970 antibody; MSE1 antibody; Probable glutamyl tRNA synthetase; mitochondrial antibody; Probable glutamyl-tRNA synthetase antibody; RGD1307904 antibody; SYEM_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Probable glutamate--tRNA ligase, mitochondrial protein (42-166AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Related Products

EARS2 Antibodies

EARS2 Proteins

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Target Background

Function
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
Gene References into Functions
  1. This study presented that a new neurological disease, early-onset leukoencephalopathy with thalamus and brainstem involvement and high lactate, defined by a peculiar biphasic clinical course and caused by mutations in a single gene, EARS2. PMID: 22492562
Involvement in disease
Combined oxidative phosphorylation deficiency 12 (COXPD12)
Subcellular Location
Mitochondrion matrix.
Protein Families
Class-I aminoacyl-tRNA synthetase family, Glutamate--tRNA ligase type 1 subfamily
Database Links

HGNC: 29419

OMIM: 612799

KEGG: hsa:124454

STRING: 9606.ENSP00000343488

UniGene: Hs.620541

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