EBF2 Antibody

Code CSB-PA884503LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA884503LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) EBF2 Polyclonal antibody
Uniprot No.
Target Names
EBF2
Alternative Names
EBF2 antibody; COE2Transcription factor COE2 antibody; Early B-cell factor 2 antibody; EBF-2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transcription factor COE2 protein (53-254AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The EBF2 Antibody (Product code: CSB-PA884503LA01HU) is Non-conjugated. For EBF2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA884503LB01HU EBF2 Antibody, HRP conjugated ELISA
FITC CSB-PA884503LC01HU EBF2 Antibody, FITC conjugated
Biotin CSB-PA884503LD01HU EBF2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.
Gene References into Functions
  1. EBF2 gene variants can contribute to KD [ Kawasaki disease]in the Korean population. PMID: 29749135
  2. Novel inguinal hernia susceptibility genes are identified as EFEMP1, WT1, EBF2 and ADAMTS6. PMID: 26686553
  3. Blnc1 forms a ribonucleoprotein complex with transcription factor EBF2 to stimulate the thermogenic gene program. Further, Blnc1 itself is a target of EBF2, thereby forming a feedforward regulatory loop to drive adipogenesis toward thermogenic phenotype. PMID: 25002143
  4. EBF2 as a mediator of osteoprotegerin inhibition to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. PMID: 19671856
Subcellular Location
Nucleus.
Protein Families
COE family
Database Links

HGNC: 19090

OMIM: 609934

KEGG: hsa:64641

STRING: 9606.ENSP00000430241

UniGene: Hs.491292

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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