EBF2 Antibody, FITC conjugated

Code CSB-PA884503LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) EBF2 Polyclonal antibody
Uniprot No.
Target Names
EBF2
Alternative Names
EBF2 antibody; COE2Transcription factor COE2 antibody; Early B-cell factor 2 antibody; EBF-2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transcription factor COE2 protein (53-254AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.
Gene References into Functions
  1. EBF2 gene variants can contribute to KD [ Kawasaki disease]in the Korean population. PMID: 29749135
  2. Novel inguinal hernia susceptibility genes are identified as EFEMP1, WT1, EBF2 and ADAMTS6. PMID: 26686553
  3. Blnc1 forms a ribonucleoprotein complex with transcription factor EBF2 to stimulate the thermogenic gene program. Further, Blnc1 itself is a target of EBF2, thereby forming a feedforward regulatory loop to drive adipogenesis toward thermogenic phenotype. PMID: 25002143
  4. EBF2 as a mediator of osteoprotegerin inhibition to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. PMID: 19671856
Subcellular Location
Nucleus.
Protein Families
COE family
Database Links

HGNC: 19090

OMIM: 609934

KEGG: hsa:64641

STRING: 9606.ENSP00000430241

UniGene: Hs.491292

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