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EBFP Mouse Polyclonal Antibody

Datasheet
Code CSB-PA588045
Size US$258
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Product Details

Uniprot No.
Q9ULX5
Target Names
RNF112
Raised in
Mouse
Species Reactivity
N/A
Immunogen
The EBFP Mouse Polyclonal Antibody detects EBFP & EBFP Tag protein.
Clonality
Polyclonal
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Liquid
Tested Applications
WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
Protocols
Western Blotting(WB) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins. Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-induced damage. Exhibits GTPase and E3 ubiquitin-protein ligase activities. Regulates dendritic spine density and synaptic neurotransmission; its ability to hydrolyze GTP is involved in the maintenance of dendritic spine density.
Subcellular Location
Membrane; Multi-pass membrane protein. Membrane; Peripheral membrane protein. Cytoplasm. Nucleus. Nucleus, nuclear body. Nucleus, nucleoplasm. Endosome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Cell junction, synapse, postsynaptic density. Perikaryon. Cell projection, neuron projection.
Protein Families
TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3-type GTPase family, GB1 subfamily
Tissue Specificity
Predominantly expressed in brain. Decreased expression in glioma brain tumors as compared to normal brains (at protein level).
Database Links

HGNC: 12968

OMIM: 601237

KEGG: hsa:7732

STRING: 9606.ENSP00000454919

UniGene: Hs.189482

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