EHHADH Antibody

Code CSB-PA600104LA01HU
Size US$166
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  • Western blot
    All lanes: EHHADH antibody at 2µg/ml + Mouse kidney tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 80, 70 kDa
    Observed band size: 80 kDa

  • Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA600104LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA600104LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) EHHADH Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
3 hydroxyacyl CoA dehydrogenase antibody; 3,2 trans enoyl CoA isomerase antibody; 3-hydroxyacyl-CoA dehydrogenase antibody; ECHD antibody; ECHP_HUMAN antibody; EHHADH antibody; Enoyl Coenzyme A antibody; Enoyl Coenzyme A; hydratase/3 hydroxyacyl Coenzyme A dehydrogenase antibody; L 3 hydroxyacyl CoA dehydrogenase antibody; L bifunctional protein antibody; L bifunctional protein; peroxisomal antibody; L PBE antibody; LBFP antibody; LBP antibody; MGC120586 antibody; MS730 antibody; PBE antibody; PBFE antibody; Peroxisomal bifunctional enzyme antibody; Peroxisomal enoyl CoA hydratase antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Peroxisomal bifunctional enzyme protein (1-723AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The EHHADH Antibody (Product code: CSB-PA600104LA01HU) is Non-conjugated. For EHHADH Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA600104LB01HU EHHADH Antibody, HRP conjugated ELISA
FITC CSB-PA600104LC01HU EHHADH Antibody, FITC conjugated
Biotin CSB-PA600104LD01HU EHHADH Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Peroxisomal trifunctional enzyme possessing 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and delta 3, delta 2-enoyl-CoA isomerase activities. Catalyzes two of the four reactions of the long straight chain fatty acids peroxisomal beta-oxidation pathway. Optimal isomerase for 2,5 double bonds into 3,5 form isomerization in a range of enoyl-CoA species (Probable). Also able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. With HSD17B4, catalyzes the hydration of trans-2-enoyl-CoA and the dehydrogenation of 3-hydroxyacyl-CoA, but with opposite chiral specificity. Regulates the amount of medium-chain dicarboxylic fatty acids which are essential regulators of all fatty acid oxidation pathways. Also involved in the degradation of long-chain dicarboxylic acids through peroxisomal beta-oxidation.
Gene References into Functions
  1. Mistargeting of peroxisomal EHHADH disrupts mitochondrial metabolism and leads to renal Fanconi's syndrome; this indicates a central role of mitochondria in proximal tubular function. PMID: 24401050
Involvement in disease
Fanconi renotubular syndrome 3 (FRTS3)
Subcellular Location
Peroxisome.
Protein Families
Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase family
Tissue Specificity
Liver and kidney. Strongly expressed in the terminal segments of the proximal tubule. Lower amounts seen in the brain.
Database Links

HGNC: 3247

OMIM: 607037

KEGG: hsa:1962

STRING: 9606.ENSP00000231887

UniGene: Hs.429879

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