EIF2B3 Antibody

Code CSB-PA007516GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
EIF2B3
Alternative Names
EI2BG_HUMAN antibody; EIF 2B antibody; eIF 2B GDP GTP exchange factor subunit gamma antibody; eIF-2B GDP-GTP exchange factor subunit gamma antibody; eIF2B-gamma antibody; Eif2b3 antibody; EIF2Bgamma antibody; Eukaryotic translation initiation factor 2B subunit 3 gamma antibody; Eukaryotic translation initiation factor 2B; gamma antibody; eukaryotic translation initiation factor 2B; subunit 3 gamma; 58kDa antibody; OTTHUMP00000010262 antibody; OTTHUMP00000010263 antibody; Translation initiation factor eIF-2B subunit gamma antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human EIF2B3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
Gene References into Functions
  1. To determine the tolerance differences to ERS, cell viability and apoptosis rates were detected in oligodendrocyte cell lines transfected with EIF2B3-c.1037T>C or the wild type. We confirmed that oligodendrocytes with mutant EIF2B3 was less tolerant to ERS than the wild type, with decreased cell viability and increased apoptosis rates. PMID: 26625702
  2. Results show significant higher incidence of Chinese patients with EIF2B3 mutations compared with Caucasian patients. The c.1037T>C in EIF2B3 was confirmed to be a founder mutation in Chinese explaining the genotypic differences between ethnicities. PMID: 25761052
Involvement in disease
Leukodystrophy with vanishing white matter (VWM)
Protein Families
EIF-2B gamma/epsilon subunits family
Database Links

HGNC: 3259

OMIM: 603896

KEGG: hsa:8891

STRING: 9606.ENSP00000353575

UniGene: Hs.533549

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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