EIF4H Antibody

1. The results from these procedures revealed eIF4H to be one of the targets of miR-519d. Downregulated eIF4H was analogous to the overexpressed miR-519d obtained from miR-519d agomir and si-eIF4H transfection. In summary, it can be concluded that miR-519d targets eIF4H in lung adenocarcinoma to inhibit cell proliferation and invasion PMID: 28351305
2. Results demonstrate that eukaryotic translation initiation factor 4H (eIF4H) plays a crucial role in translational control. PMID: 26498689
3. Eukaryotic Initiation Factor 4H Is under Transcriptional Control of p65/NF-kappaB. PMID: 23776612
4. Studies indicate that eIF4A (DDX2), together with its accessory proteins eIF4B and eIF4H, is thought to act as a helicase that unwinds secondary structures in the mRNA 5' UTR. PMID: 21427765
5. results suggest that eIF4H isoform 1 plays an important role in carcinogenesis through the activation of oncogenic signaling and could be a promising molecular target for cancer therapy PMID: 20473909
6. data indicate that eIF4B and 4H stimulate the nuclease activity of herpes simplex virus vhs, and they provide evidence that additional mammalian factors are required for targeting to the encephalomyocarditis virus IRES PMID: 15078951
7. eIF4H binding is required for herpes simplex virus virion host shutoff-induced degradation of many mRNAs, perhaps by targeting Vhs to mRNAs and to preferred sites within mRNAs. PMID: 18448541
8. The interaction of eIF4AI with two accessory factors, eIF4B and eIF4H, was studied. PMID: 18719248
9. Study reports the topology of the eIF4A/4G/4H helicase complex, which is built from multiple experimentally observed domain-domain contacts. PMID: 19203580
10. Data show that reduced levels of eIF4B, eIF4H, or polyA-binding protein, also trigger SG formation. PMID: 19369421

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HGNC: 12741

OMIM: 603431

KEGG: hsa:7458

STRING: 9606.ENSP00000265753

UniGene: Hs.520943