ELF2 Antibody

1. Mutations in eIF2B genes cause vanishing white matter disease due to translation defects. PMID: 29632131
2. Our findings collectively support a potential role of triiodothyronine and its receptor in tumor growth inhibition through regulation of ELF2 PMID: 26968954
3. PCAT7 contributed to the progression of nasopharyngeal carcinoma through regulating miR-134-5p/ELF2 signaling pathway. PMID: 28728844
4. angiopoietin-1 regulates expression of NERF2 and its own receptor in hypoxic cells. PMID: 11967990
5. NERF/ELF-2 physically interacts with AML1 and mediates opposing effects on AML1-mediated transcription of the B cell-specific blk gene PMID: 14970218
6. These findings indicate that ELF2/NERF promotes VCP transcription and that ELF2/NERF-VCP pathway might be important for cell survival and proliferation under cytokine stress. PMID: 17368566
7. ELF2 transactivates VCP promoter through binding to two motifs, with a predominant contribution of the upstream one. PMID: 18544453
8. Affinity of the CAL PDZ domain for the cystic fibrosis transmembrane conductance regulator (CFTR) C-terminus is much weaker than that of the NHERF1/NHERF2 domains, enabling wild-type CFTR to avoid premature entrapment in the lysosomal pathway. PMID: 18754678

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HGNC: 3317

KEGG: hsa:1998

STRING: 9606.ENSP00000265495

UniGene: Hs.634040