ENTPD3 Antibody

Code CSB-PA007692GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ENTPD3
Alternative Names
ATPDase antibody; CD39 antigen like 3 antibody; CD39 antigen-like 3 antibody; CD39 like 3 antibody; CD39L3 antibody; Ecto apyrase antibody; Ecto ATP diphosphohydrolase antibody; Ecto-apyrase 3 antibody; Ecto-ATP diphosphohydrolase 3 antibody; Ecto-ATPase 3 antibody; Ecto-ATPDase 3 antibody; Ectonucleoside triphosphate diphosphohydrolase 3 antibody; ENTP3_HUMAN antibody; ENTPD 3 antibody; ENTPD3 antibody; FLJ93839 antibody; HB 6 antibody; HB6 antibody; NTPDase 3 antibody; NTPDase3 antibody; OTTHUMP00000162079 antibody; OTTHUMP00000209227 antibody; OTTHUMP00000209228 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human ENTPD3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Has a threefold preference for the hydrolysis of ATP over ADP.
Gene References into Functions
  1. NTPDase3 is the major ectonucleotidase in pancreatic beta-cells in multiple species and modulates insulin secretion by controlling activation of purinergic receptors. PMID: 24085034
  2. NTPDase3 sequence revealed a high degree of structural fold similarity with a bacterial exopolyphosphatase PMID: 15966724
  3. efficiently inhibit the NTPDase3expressed in insulin secreting human pancreatic islet cells in situ PMID: 19120451
  4. Generation of a helical model for NTPDase3 suggests the importance of putative hydrogen bond interactions of conserved polar residues which are critical for enzyme expression, activity, and its susceptibility to membrane perturbations. PMID: 19743837
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
GDA1/CD39 NTPase family
Tissue Specificity
Expressed in adult brain, pancreas, spleen and prostate. Moderate or low expression is seen in most tissues. Not expressed in liver and peripheral blood leukocytes.
Database Links

HGNC: 3365

OMIM: 603161

KEGG: hsa:956

STRING: 9606.ENSP00000301825

UniGene: Hs.441145

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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