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EPSTI1 Antibody, HRP conjugated

Datasheet
Code CSB-PA839347LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) EPSTI1 Polyclonal antibody
Uniprot No.
Q96J88
Target Names
EPSTI1
Alternative Names
BRESI 1 antibody; BRESI1 antibody; Epithelial stromal interaction 1 (breast) antibody; Epithelial stromal interaction protein 1 (breast) antibody; Epithelial stromal interaction protein 1 antibody; Epithelial-stromal interaction protein 1 antibody; EPSTI 1 antibody; Epsti1 antibody; ESIP1_HUMAN antibody; MGC29634 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Epithelial-stromal interaction protein 1 protein (12-56AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation. Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages.
Gene References into Functions
  1. A novel KLF8 to EPSTI1 to VCP to NF-kappaB signaling mechanism potentially critical for breast cancer invasion and metastasis. PMID: 24096480
  2. These observations implicate EPSTI1 as a hitherto unappreciated regulator of tumor cell properties. PMID: 20133812
Tissue Specificity
Highly expressed in placenta, small intestine, spleen, kidney, thymus, liver, salivary gland and testes. Weakly expressed in breast, skeletal muscle and colon. Highly expressed in breast cancer upon interaction between tumor cells and stromal cells in vit
Database Links

HGNC: 16465

OMIM: 607441

KEGG: hsa:94240

STRING: 9606.ENSP00000318982

UniGene: Hs.546467

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