EPSTI1 Antibody

Code CSB-PA964117
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA964117(EPSTI1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA964117(EPSTI1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human placenta tissue, Primary antibody: CSB-PA964117(EPSTI1 Antibody) at dilution 1/1900, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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Product Details

Uniprot No.
Target Names
EPSTI1
Alternative Names
BRESI 1 antibody; BRESI1 antibody; Epithelial stromal interaction 1 (breast) antibody; Epithelial stromal interaction protein 1 (breast) antibody; Epithelial stromal interaction protein 1 antibody; Epithelial-stromal interaction protein 1 antibody; EPSTI 1 antibody; Epsti1 antibody; ESIP1_HUMAN antibody; MGC29634 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Fusion protein of Human EPSTI1
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:10000
WB 1:1000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation. Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages.
Gene References into Functions
  1. A novel KLF8 to EPSTI1 to VCP to NF-kappaB signaling mechanism potentially critical for breast cancer invasion and metastasis. PMID: 24096480
  2. These observations implicate EPSTI1 as a hitherto unappreciated regulator of tumor cell properties. PMID: 20133812
Tissue Specificity
Highly expressed in placenta, small intestine, spleen, kidney, thymus, liver, salivary gland and testes. Weakly expressed in breast, skeletal muscle and colon. Highly expressed in breast cancer upon interaction between tumor cells and stromal cells in vit
Database Links

HGNC: 16465

OMIM: 607441

KEGG: hsa:94240

STRING: 9606.ENSP00000318982

UniGene: Hs.546467

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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