ERGIC3 Antibody

Code CSB-PA030013
Size US$100
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Product Details

Uniprot No.
Target Names
ERGIC3
Alternative Names
2310015B14Rik antibody; AV318804 antibody; C20orf47 antibody; CGI 54 antibody; D2Ucla1 antibody; dJ477O4.2 antibody; DKFZp547A2190 antibody; Endoplasmic reticulum Golgi intermediate compartment protein 3 antibody; endoplasmic reticulum localized protein ERp43 antibody; Endoplasmic reticulum-Golgi intermediate compartment protein 3 antibody; ERGI3_HUMAN antibody; ERGIC and golgi 3 antibody; ergic3 antibody; ERV46 antibody; NY BR 84 antibody; PRO0989 antibody; RP23-220D12.2 antibody; RP3-477O4.1 antibody; SDBCAG84 antibody; Serologically defined breast cancer antigen 84 antibody; Serologically defined breast cancer antigen NY BR 84 antibody; Serologically defined breast cancer antigen NY-BR-84 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from the C-terminal region of Human ERGIC-3.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Possible role in transport between endoplasmic reticulum and Golgi.
Gene References into Functions
  1. these data showed that knockdown of ERGIC3 triggers endoplasmic reticulum stress-induced autophagic cancer cell death PMID: 27588471
  2. Results showed that miR-203a downregulation induced ERGIC3 overexpression in non-small cell lung cancer cells. PMID: 26177443
  3. ERGIC3 may play an active role in the development and progression of lung cancer. PMID: 23374247
  4. miR-490-3p modulates cell growth and epithelial to mesenchymal transition of hepatocellular carcinoma cells by targeting endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3). PMID: 23212913
  5. Plays important roles in cell growth and endoplasmic reticulum stress-induced cell death. PMID: 17020792

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Subcellular Location
Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Cycles between the endoplasmic reticulum and the Golgi.
Protein Families
ERGIC family
Database Links

HGNC: 15927

KEGG: hsa:51614

STRING: 9606.ENSP00000349970

UniGene: Hs.472558

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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