EVA1A Antibody

Code CSB-PA913716
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA913716(EVA1A Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
EVA1A
Alternative Names
EVA1A; FAM176A; TMEM166; SP24; Protein eva-1 homolog A; Protein FAM176A; Transmembrane protein 166
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide of Human EVA1A
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.
Gene References into Functions
  1. Low EVA1A expression is associated with glioblastoma. PMID: 28185834
  2. The adenovirus-mediated increase of FAM176A inhibited the growth of the tumor cells. PMID: 24257118
  3. TMEM166 expression was widely down-regulated in the cancer tissues. PMID: 22495369
  4. Low TMEM166 mRNA and protein expression is associated with esophageal squamous cell carcinoma. PMID: 23098460
  5. TMEM166 is a novel regulator involved in both autophagy and apoptosis. PMID: 17492404

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Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein.
Protein Families
EVA1 family
Tissue Specificity
Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.
Database Links

HGNC: 25816

KEGG: hsa:84141

STRING: 9606.ENSP00000233712

UniGene: Hs.302346

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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