EXOC1 Antibody

1. rs13117307 is associated with cervical squamous cell carcinoma. rs13117307 SNP upregulated EXCO1 transcript levels in the non-cancerous cervical and in the cervical SCC tissue. PMID: 28694212
2. Ezrin/Sec3 complexes are essential for MUC5AC secretion in NE-stimulated airway epithelial cells and that PIP2 is of critical importance in the formation of these complexes. PMID: 25591774
3. This study portrayed the non-structural function of C protein that helped the flavivirus to nullify the antiviral activity of hSec3p by accelerating its degradation and facilitating efficient binding of elongation factor 1alpha with flaviviral RNA genome. PMID: 23522008
4. This study identified human Sec3 exocyst protein (hSec3p) as a novel interacting partner of West Nile virus and Dengue virus C protein. PMID: 19889084
5. Sec3 associates with a subset of Exocyst complexes that are enriched at desmosomes. PMID: 19889837
6. The exocyst subunits Sec3 and Sec8 interact with the polarity protein IQGAP1 and that this interaction is triggered by active Cdc42 and RhoA, which are essential for matrix degradation. PMID: 18541705

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HGNC: 30380

OMIM: 607879

KEGG: hsa:55763

STRING: 9606.ENSP00000326514

UniGene: Hs.269665