EXOC5 Antibody

Code CSB-PA007883GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
EXOC5
Alternative Names
EXOC5 antibody; SEC10 antibody; SEC10L1Exocyst complex component 5 antibody; Exocyst complex component Sec10 antibody; hSec10 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human EXOC5
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Gene References into Functions
  1. These data confirm that the exocyst is preferentially involved in basolateral protein translation and translocation, and may well act through the phosphorylation of Sec61beta. PMID: 23037926
  2. Suggest that the exocyst sec10, acting through EGFR, endocytosis, and the MAPK pathway is a candidate therapeutic target for acute kidney injury. PMID: 25298525
  3. Exocyst Sec10 overexpression reduces damage to tubular epithelial barriers caused by hydrogen peroxide and speeds the recovery of normal epithelial barrier function after such an injury. PMID: 20053792
  4. Data show that GTP-bound ARF6 interacts with Sec10, a subunit of the exocyst complex involved in docking of vesicles with the plasma membrane. PMID: 14662749
  5. The exocyst protein Sec10 regulates primary ciliogenesis. PMID: 19297529

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Subcellular Location
Cytoplasm. Midbody.
Protein Families
SEC10 family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 10696

OMIM: 604469

KEGG: hsa:10640

STRING: 9606.ENSP00000389934

UniGene: Hs.743987

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