FAM120A Antibody

Datasheet

Code	CSB-PA008027GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9NZB2

Target Names

FAM120A

Alternative Names

C9orf10 antibody; Chromosome 9 open reading frame 10 antibody; Constitutive coactivator of PPAR gamma like protein 1 antibody; Constitutive coactivator of PPAR-gamma-like protein 1 antibody; DNA polymerase transactivated protein 5 antibody; DNA polymerase transactivated protein 1 antibody; DNAPTP1 antibody; DNAPTP5 antibody; F120A_HUMAN antibody; FAM120A antibody; Family with sequence similarity 120A antibody; Hypothetical protein LOC23196 antibody; KIAA0183 antibody; LOC23196 antibody; MGC111527 antibody; MGC133257 antibody; OSSA antibody; Oxidative stress-associated Src activator antibody; Protein FAM120A antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human FAM120A

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

May participate in mRNA transport in the cytoplasm. Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.

Gene References into Functions

his study shows that widespread structural brain involvement is not limited to C9+ patients, but also presents in a subgroup of C9- patients with ALS and relates to cognitive deficits. Our neuroimaging findings reveal an intermediate phenotype that may provide insight into the complex relationship between genetic factors and clinical characteristics. PMID: 27756805
Results identify novel SNP in FAM120A on chromosome 9 associated with differences in BMI in childhood which may predispose obesity. PMID: 25953783
Results identified FAM120A in the IL13/IL13Ralpha2 signaling pathway as a key mediator of invasion and liver metastasis in colon cancer. PMID: 25896327
study reports that C9orf10 (designated Ossa for oxidative stress-associated Src activator) is a novel RNA-binding protein that guards cancer cells from oxidative stress-induced apoptosis by activation of Src family kinases PMID: 19015244

Subcellular Location

Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocates to plasma membrane upon ultraviolet exposure.

Protein Families

Constitutive coactivator of PPAR-gamma family

Tissue Specificity

Ubiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level).

Database Links

HGNC: 13247

OMIM: 612265

KEGG: hsa:23196

STRING: 9606.ENSP00000277165

UniGene: Hs.372003

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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