FASTKD3 Antibody

Code CSB-PA584566
Size US$166
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Image
  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Raji cells, Primary antibody: CSB-PA584566(FASTKD3 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Product Details

Uniprot No.
Target Names
FASTKD3
Alternative Names
FASTKD3FAST kinase domain-containing protein 3 antibody; mitochondrial antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Fusion protein of Human FASTKD3
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
WB 1:200-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for normal mitochondrial respiration. Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity.
Gene References into Functions
  1. FASTKD3 is required for efficient COX1 mRNA translation without altering mRNA levels, which results in a decrease in the steady-state levels of COX1 protein. PMID: 27789713
  2. these results introduce FASTKD3 as an essential component of mitochondrial respiration that may modulate energy balance in cells exposed to adverse conditions by functionally coupling mitochondrial protein synthesis to respiration. PMID: 20869947
Subcellular Location
Mitochondrion.
Protein Families
FAST kinase family
Tissue Specificity
Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in liver and thyroid.
Database Links

HGNC: 28758

OMIM: 617530

KEGG: hsa:79072

STRING: 9606.ENSP00000264669

UniGene: Hs.653162

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