FBLN2 Antibody, Biotin conjugated

Datasheet

Code	CSB-PA008453LD01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) FBLN2 Polyclonal antibody

Uniprot No.

P98095

Target Names

FBLN2

Alternative Names

Fbln2 antibody; FBLN2_HUMAN antibody; FIBL-2 antibody; Fibulin-2 antibody; OTTHUMP00000216670 antibody; OTTHUMP00000216671 antibody; OTTHUMP00000216672 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Fibulin-2 protein (301-440AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN.

Gene References into Functions

Using in vitro approaches and cultured breast cancer cell lines authors demonstrate that Fibulin-2 is a better substrate for ADAMTS-5 than it is for ADAMTS-4. Fibulin-2 degradation is associated to an enhancement of the invasive potential of T47D, MCF-7 and SK-BR-3 cells. PMID: 28099917
levels of fibulin 2 dramatically increased in the retinal pigment epithelium following retinal detachment, suggesting a direct role for fibulin 2 in the re-attachment of the retina to the retinal pigment epithelium. PMID: 24692557
Study identified and validated a novel bona fide target of miR-1, Fibullin-2 (Fbln2), a secreted protein implicated in extracellular matrix remodeling. PMID: 23612897
Two variants in the fibulin2 gene are associated with lower systolic blood pressure and decreased risk of hypertension. PMID: 22912785
Data provide evidence that FBLN2 short isoform (FBLN2S) has an important tumor-suppressive and anti-angiogenic role in nasopharyngeal carcinoma (NPC). PMID: 21743496

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Subcellular Location

Secreted, extracellular space, extracellular matrix.

Protein Families

Fibulin family

Tissue Specificity

Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.

Database Links

HGNC: 3601

OMIM: 135821

KEGG: hsa:2199

STRING: 9606.ENSP00000384169

UniGene: Hs.198862

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Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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