FBXL14 Antibody

Code CSB-PA008465GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
FBXL14
Alternative Names
FBXL14 antibody; FBL14F-box/LRR-repeat protein 14 antibody; F-box and leucine-rich repeat protein 14 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human FBXL14
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1.
Gene References into Functions
  1. USP13 and FBXL14 play opposing roles in the regulation of glioma stem cells (GSCs) through reversible ubiquitination of c-Myc. PMID: 27923907
  2. Data show that Twist1 small interfering RNA prevents hypoxia-induced Fbxl14 down-regulation and SNAIL1 stabilization. PMID: 19955572
Subcellular Location
Cytoplasm.
Database Links

HGNC: 28624

OMIM: 609081

KEGG: hsa:144699

STRING: 9606.ENSP00000344855

UniGene: Hs.367956

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7505 Fannin St., Ste 610, Room 322 (CUBIO Innovation Center), Houston, TX 77054, USA
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