FBXL20 Antibody, HRP conjugated

Code CSB-PA822228LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FBXL20 Polyclonal antibody
Uniprot No.
Target Names
FBXL20
Alternative Names
FBXL20 antibody; FBL2F-box/LRR-repeat protein 20 antibody; F-box and leucine-rich repeat protein 20 antibody; F-box/LRR-repeat protein 2-like antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human F-box/LRR-repeat protein 20 protein (1-137AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission.
Gene References into Functions
  1. which provides a signal to promote its ubiquitination and proteasomal degradation mediated by FBXL20 and the associated Skp1-Cullin1 complex, leading to inhibition of autophagy and receptor endocytosis PMID: 25593308
  2. study concludes FBXL20 plays an essential role in the carcinogenesis of colorectal adenocarcinoma and promotes carcinogenesis through the regulation of the Wnt signaling pathway and caspase activation PMID: 23023584
Subcellular Location
Cytoplasm.
Database Links

HGNC: 24679

OMIM: 609086

KEGG: hsa:84961

STRING: 9606.ENSP00000264658

UniGene: Hs.462946

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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