FBXL21 Antibody, Biotin conjugated

Code CSB-PA891953LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FBXL21 Polyclonal antibody
Uniprot No.
Target Names
FBXL21
Alternative Names
F box and leucine rich repeat protein 21 antibody; F box and leucine rich repeat protein 3 pseudogene antibody; F box and leucine rich repeat protein 3B antibody; F box protein Fbl3b antibody; F box/LRR repeat protein 21 antibody; F box/LRR repeat protein 3B antibody; F-box and leucine-rich repeat protein 21 antibody; F-box and leucine-rich repeat protein 3B antibody; F-box/LRR-repeat protein 21 antibody; F-box/LRR-repeat protein 3B antibody; Fbl 21 antibody; FBL 3 antibody; FBL 3B antibody; Fbl21 antibody; FBL3 antibody; FBL3B antibody; FBXL 21 antibody; FBXL 3B antibody; FBXL 3P antibody; Fbxl21 antibody; FBXL3B antibody; FBXL3P antibody; FXL21_HUMAN antibody; MGC120237 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human F-box/LRR-repeat protein 21 protein (78-137AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Substrate-recognition component of the SCF(FBXL21) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL21) complex mainly acts in the cytosol and mediates ubiquitination of CRY proteins (CRY1 and CRY2), leading to CRY proteins stabilization. The SCF(FBXL21) complex counteracts the activity of the SCF(FBXL3) complex and protects CRY proteins from degradation. Involved in the hypothalamic suprachiasmatic nucleus (SCN) clock regulating temporal organization of the daily activities.
Subcellular Location
Cytoplasm, cytosol. Nucleus.
Database Links

HGNC: 13600

OMIM: 609087

UniGene: Hs.591275

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