FBXO8 Antibody

Datasheet

Code	CSB-PA008517GA01HU
Size	$600
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Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9NRD0

Target Names

FBXO8

Alternative Names

DC10 antibody; F box only protein 8 antibody; F box protein 8 antibody; F box protein Fbx8 antibody; F box/SEC7 protein FBS antibody; F-box only protein 8 antibody; F-box/SEC7 protein FBS antibody; FBS antibody; FBX8 antibody; FBX8_HUMAN antibody; FBXO 8 antibody; Fbxo8 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human FBXO8

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential).

Gene References into Functions

Study demonstrates that down-regulation of FBX8 in hepatocellular carcinoma (HCC) correlates with poor survival of patients. All of the functional experiments confirm FBX8 as a tumor suppressor in the progression of HCC. The preferential down-regulation of FBX8 in HCC patients with invasion and metastasis suggested that FBX8 may be a significant biomarker for HCC progression. PMID: 23826080
FBX8 as a metastasis suppressor that functions through mTOR signaling pathway and has significant prognostic power. PMID: 27916606
FBX8 down-expression was an independent prognostic indicator for glioma patient's survival. PMID: 25550853
FBX8 was markedly down-regulated in gastric cancer tissues. Knocking down FBX8 promoted proliferation and invasion in tumor cell line. Patients with low FBX8 had poor prognosis. PMID: 25801334
FBX8 is a novel c-Myc binding protein and that c-Myc induces cell invasive activity PMID: 20848231

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Database Links

HGNC: 13587

OMIM: 605649

KEGG: hsa:26269

STRING: 9606.ENSP00000377280

UniGene: Hs.76917

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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