FCRL3 Antibody, Biotin conjugated

1. no association between the FCRL-3 rs7528684 SNP with susceptibility to allergic asthma in Iranian North-Western Azeri population. PMID: 28792713
2. -169CC genotype associated with a beneficial functional effect on residual insulin secretion and HbA1c level dynamics in type 1 diabetes PMID: 27615679
3. Pooled genome wide association study identified a genetic variant upstream of FCRL3 as a susceptibility locus for Graves' disease in addition to those identified in the Major Histo-compatibility Complex. PMID: 27863461
4. The expression of Sezary signature genes: FCRL3, Tox, and miR-214, was significantly higher in samples from Sezary syndrome patients with CD164 expressing CD4(+) T cells. PMID: 27766406
5. This study aims to investigate the association between common polymorphisms of FCRL3 gene and multiple sclerosis risk in a Chinese Han population. PMID: 25862376
6. Observed no association between the MHC2TA or FCRL3 SNPs and rheumatoid arthritis in Mexican patients. PMID: 26350270
7. genetic polymorphism is associated with rheumatoid arthritis in Chinese Han population PMID: 26746625
8. Genetic polymorphisms in FCRL3 are genetic risk factors for neuromyelitis optica in the Chinese population. PMID: 25575677
9. FCRL3_3, FCRL3_5 and FCRL3_6 polymorphisms could increase susceptibility to Graves' disease only in Asians, rather than in Caucasians. PMID: 26321232
10. CTLA4 and FCRL3 genes overexpression may play an important role in children suffering from autoimmune thyroiditis. PMID: 26994388
11. FCRL3 genetic polymorphisms were associated with an increased risk of endometriosis-related infertility, regardless of symptoms. PMID: 26334889
12. 4 Single Nucleotide Polymorphisms (rs7528684, rs945635, rs3761959, and rs2282284) could significantly elevate the risk of Neuromyelitis Optica in Chinese Han population. PMID: 26402798
13. study found a significant association between the SNPs in FCRL3 gene and allergic rhinitis (AR) in Chinese Han patients; results suggest these gene polymorphisms might be the autoimmunity risk for AR PMID: 25594855
14. Association between FCRL3 polymorphisms and increased risk of sudden sensorineural hearing loss in a Chinese Han population. PMID: 26051414
15. the TIGIT/FCRL3 combination allows reliable identification of Helios(+) Treg cells even in highly activated conditions in vitro as well as in PBMCs of autoimmune patients. PMID: 25762785
16. CONCLUSIONS: Our study demonstrated that the FCRL3 -169T>C polymorphism is not a risk factor of systemic lupus erythematosus in the Polish population, but this polymorphism may contribute to autoantibody production in this disease. PMID: 24593204
17. the FCRL3 polymorphisms are associated with not only autoimmune diseases including RA, GD, T1D, and other disease under different genetic models, but also different ethnic subgroups. PMID: 24117236
18. meta-analysis of published studies including 2,544 patients and 3,913 controls demonstrates that the FCRL3 -169 C/T polymorphism does not confer susceptibility to systemic lupus erythematosus in Europeans or Asians PMID: 23512175
19. FCRL3 -169T>C polymorphism alters the expression of FCRL3 and can be a risk factor of endometriosis-related infertility. PMID: 23553198
20. This meta-analysis demonstrates that the FCRL3 -169 C/T polymorphism may confer susceptibility to seropositive RA in Asians.[meta-analysis] PMID: 23777926
21. The results of this study showed a significant association between FCRL3-110 A/G polymorphism and susceptibility to rheumatoid arthritis. PMID: 23883198
22. FCRL3 amplified the NF-kappaB and mitogen-activated protein kinase signaling cascades, and halted CpG triggered BLIMP1 induction in an ERK-dependent fashion. PMID: 23857366
23. FCRL3 gene polymorphism shows positive relatationship in the development of rheumatoid arthritis. PMID: 23463945
24. FCRL3 gene and its proxy SNP rs7528684 may be involved in the pathogenesis of GD by excessive inhibiting B cell receptor signaling and the impairment of suppressing function of Tregs. PMID: 23505439
25. CD40 and FCRL3 gene polymorphisms were associated with autoimmune hyperthyroidism intractability. PMID: 22706687
26. A male-gender juvenile rheumatoid arthritis and asthma, but not childhood-onset systemic lupus erythematosus are associated with FCRL3 polymorphisms in Mexicans. PMID: 23070121
27. Polymorphisms of the FCRL3 gene may contribute to the progression of joint destruction rather than susceptibility to rheumatoid arthritis. PMID: 22386693
28. A functional variant in FCRL3 is associated with higher Fc receptor-like 3 expression on T cell subsets and rheumatoid arthritis disease activity. PMID: 22392608
29. Findings support a possible gene-gene interaction for FOXP3/FCRL3 polymorphisms, leading to a cumulative effect on endometriosis development. PMID: 22341374
30. Frequencies of specific FcRL3 haplotypes are significantly associated with a Chinese cohort of Guillain-Barre syndrome patients compared with healthy controls. PMID: 22458979
31. FCRL3 -169C/C genotype is associated with anti-citrullinated protein antibody-positive rheumatoid arthritis and with radiographic progression. PMID: 21885492
32. genetic polymorphism is associated with endometriosis in Brazilian population PMID: 21663782
33. the FCRL3 C-169T polymorphism may play an important role in the pathogenesis of endometriosis and/or infertility. PMID: 21529967
34. The functional FCRL3 SNP -169T/C appears to play important roles in the development of certain phenotypes such as systemic lupus erythematosus leukopenia and rheumatoid arthritis disease severity in Taiwanese patients with these diseases. PMID: 21078711
35. A significant association of fcrl3_3 with primary biliary cirrhosis only in Japanese. PMID: 21299530
36. These results suggest that FCRL3 polymorphisms and haplotypes may contribute to genetic susceptibility to rheumatoid arthritis in a Chinese population. PMID: 20732364
37. PTPN22 rs3789604 and FCRL3 rs7528684 polymorphisms are protective against Graves' disease. PMID: 19438904
38. Meta-analysis suggests that the FCRL3 -169 C/T polymorphism is a significant risk factor for rheumatoid arthritis in Asians, but not in Europeans. PMID: 19690864
39. FcRL3 expression is associated with T(reg) dysfunction PMID: 20190142
40. The polymorphisms of the promoter A/G,exon 2 C/G,exon 4 C/T in the FcRL3 gene were risk factors to Graves disease in Chongqing Han population. PMID: 19953494
41. The FCRL3 gene does not appear associated with susceptibility to HLA-B27-positive ankylosing spondylitis in Han Chinese population. PMID: 19657722
42. This meta-analysis demonstrates that the FCRL3 169CC genotype (recessive effect) may confer susceptibility to systemic lupus erythematosus, especially in Asian-derived population. PMID: 19565352
43. molecular cloning and characterization of SPAP2 PMID: 12051764
44. Single nucleotide polymorphism in Graves' disease in a large UK Caucasian Graves' disease data set. PMID: 16384851
45. This gene will not have a substantial effect in determining susceptibility to RArheumatoid arthritis in populations of Northern European descent. PMID: 16859508
46. Susceptibility to type 1 autoimmune hepatitis in Japanese patients is not influenced by FcgammaRIIA, FcgammaRIIB, or FCRL3 polymorphisms. PMID: 17020818
47. Findings from a large case-control sample of patients with alopecia areata (AA) do not support an association between FCRL3 and susceptibility to AA. PMID: 17117947
48. Both the FCRL3 and PTPN22 genes play roles in rheumatoid arthritis susceptibility, but in different individuals. PMID: 17133579
49. The association of the -169C/T SNP in FCRL3 with rheumatoid arthritis and systemic lupus erythematosus that was observed in Japanese patients was not replicated in a Korean population. PMID: 17133581
50. Susceptibility to autoimmunity at the FCRL3 locus. PMID: 17200162

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HGNC: 18506

OMIM: 180300

KEGG: hsa:115352

STRING: 9606.ENSP00000357167

UniGene: Hs.292449