FHOD1 Antibody, Biotin conjugated

Datasheet
Code CSB-PA896540LD01HU
Size US$299
Uniprot No. Q9Y613
Protocols ELISA Protocol
Immunogen Recombinant Human FH1/FH2 domain-containing protein 1 protein (338-437AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing.
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias FH1/FH2 domain-containing protein 1 (Formin homolog overexpressed in spleen 1) (FHOS) (Formin homology 2 domain-containing protein 1), FHOD1, FHOS FHOS1
Immunogen Species Homo sapiens (Human)
Research Area Signal Transduction
Target Names FHOD1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing.
Subcellular Location Cytoplasm, Cytoplasm, cytoskeleton, Cell projection, bleb
Protein Families Formin homology family
Tissue Specificity Ubiquitous. Highly expressed in spleen.
Database Links

HGNC: 17905

OMIM: 606881

KEGG: hsa:29109

STRING: 9606.ENSP00000258201

UniGene: Hs.95231

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