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FRYL Antibody, HRP conjugated

Datasheet
Code CSB-PA009007LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FRYL Polyclonal antibody
Uniprot No.
O94915
Target Names
FRYL
Alternative Names
2010313D22Rik antibody; 2310004H21Rik antibody; 2510002A14Rik antibody; 9030227G01Rik antibody; AF4P12 antibody; AI930088 antibody; ALL fused gene from chromosome 4p12 antibody; ALL1-fused gene from chromosome 4p12 protein antibody; DKFZp686E205 antibody; FLJ161772 antibody; FRY like antibody; FRYL antibody; FRYL_HUMAN antibody; Furry homolog like (Drosophila) antibody; Furry homolog like antibody; Furry like antibody; KIAA0826 antibody; mKIAA0826 antibody; Protein furry homolog-like antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein furry homolog-like protein (42-739AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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FRYL Antibodies

FRYL Proteins

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Target Background

Function
Plays a key role in maintaining the integrity of polarized cell extensions during morphogenesis, regulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching. May function as a transcriptional activator.
Gene References into Functions
  1. Thus, t(4;11)(p12;q23) with MLL and FRYL involvement represents a new recurring 11q23 translocation, to date seen only in therapy-related acute leukemias. PMID: 17854671
Involvement in disease
A chromosomal aberration involving FRYL is found in treatment-related acute lymphoblastic leukemia (ALL). Translocation t(4;11)(p12;q23) that forms a KMT2A/MLL1-FRYL fusion protein.
Protein Families
Furry protein family
Tissue Specificity
Widely expressed with higher expression in colon, placenta, brain and cells of lymphoid origin.
Database Links

HGNC: 29127

KEGG: hsa:285527

STRING: 9606.ENSP00000351113

UniGene: Hs.595553

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