FRYL Antibody, HRP conjugated

Code CSB-PA009007LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FRYL Polyclonal antibody
Uniprot No.
Target Names
FRYL
Alternative Names
2010313D22Rik antibody; 2310004H21Rik antibody; 2510002A14Rik antibody; 9030227G01Rik antibody; AF4P12 antibody; AI930088 antibody; ALL fused gene from chromosome 4p12 antibody; ALL1-fused gene from chromosome 4p12 protein antibody; DKFZp686E205 antibody; FLJ161772 antibody; FRY like antibody; FRYL antibody; FRYL_HUMAN antibody; Furry homolog like (Drosophila) antibody; Furry homolog like antibody; Furry like antibody; KIAA0826 antibody; mKIAA0826 antibody; Protein furry homolog-like antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein furry homolog-like protein (42-739AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a key role in maintaining the integrity of polarized cell extensions during morphogenesis, regulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching. May function as a transcriptional activator.
Gene References into Functions
  1. Thus, t(4;11)(p12;q23) with MLL and FRYL involvement represents a new recurring 11q23 translocation, to date seen only in therapy-related acute leukemias. PMID: 17854671
Involvement in disease
A chromosomal aberration involving FRYL is found in treatment-related acute lymphoblastic leukemia (ALL). Translocation t(4;11)(p12;q23) that forms a KMT2A/MLL1-FRYL fusion protein.
Protein Families
Furry protein family
Tissue Specificity
Widely expressed with higher expression in colon, placenta, brain and cells of lymphoid origin.
Database Links

HGNC: 29127

KEGG: hsa:285527

STRING: 9606.ENSP00000351113

UniGene: Hs.595553

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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