G2E3 Antibody

Code CSB-PA741972LA01HU
Size US$166
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  • Immunofluorescence staining of A549 cells with CSB-PA741972LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) G2E3 Polyclonal antibody
Uniprot No.
Target Names
G2E3
Alternative Names
G2E3 antibody; KIAA1333G2/M phase-specific E3 ubiquitin-protein ligase antibody; EC 2.3.2.26 antibody; G2/M phase-specific HECT-type E3 ubiquitin transferase antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human G2/M phase-specific E3 ubiquitin-protein ligase protein (240-337AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The G2E3 Antibody (Product code: CSB-PA741972LA01HU) is Non-conjugated. For G2E3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA741972LB01HU G2E3 Antibody, HRP conjugated ELISA
FITC CSB-PA741972LC01HU G2E3 Antibody, FITC conjugated
Biotin CSB-PA741972LD01HU G2E3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death.
Gene References into Functions
  1. Results suggest that G2E3 is a molecular determinant of the DDR and cell survival. PMID: 25593194
  2. Cell cycle phase-specific expression and highly regulated subcellular localization of G2E3 suggest a possible role in cell cycle regulation and the cellular response to DNA damage. PMID: 17239372
Subcellular Location
Nucleus, nucleolus. Cytoplasm.
Tissue Specificity
Predominantly expressed in brain, liver, kidney, testes and ovary.
Database Links

HGNC: 20338

OMIM: 611299

KEGG: hsa:55632

STRING: 9606.ENSP00000206595

UniGene: Hs.509008

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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