GABRQ Antibody

Code CSB-PA891564LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA891564LA01HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA891564LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GABRQ Polyclonal antibody
Uniprot No.
Target Names
GABRQ
Alternative Names
GABRQ antibody; Gamma-aminobutyric acid receptor subunit theta antibody; GABA(A) receptor subunit theta antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Gamma-aminobutyric acid receptor subunit theta protein (348-611AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The GABRQ Antibody (Product code: CSB-PA891564LA01HU) is Non-conjugated. For GABRQ Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA891564LB01HU GABRQ Antibody, HRP conjugated ELISA
FITC CSB-PA891564LC01HU GABRQ Antibody, FITC conjugated
Biotin CSB-PA891564LD01HU GABRQ Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Gene References into Functions
  1. We identified truncating mutations in distinct X-linked gamma-aminobutyric acid A (GABAA) receptor subunit-encoding genes, GABRQ and GABRA3.this is the first report of ASD patients with truncating mutations in GABA receptors genes. PMID: 23169495
  2. GABRQ plays important roles in hepatocellular carcinoma development and progression PMID: 22690081
  3. single nucleotide polymorphisms studied in the GABRA4, GABRE, and GABRQ genes are not related to the risk for familial ET. PMID: 21422964
  4. Although GABRQ genes did not show positive association, further studies are necessary to consider the role of other GABA receptor genes in migraine susceptibility PMID: 19087248
Subcellular Location
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein Families
Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRQ sub-subfamily
Database Links

HGNC: 14454

OMIM: 300349

KEGG: hsa:55879

STRING: 9606.ENSP00000359329

UniGene: Hs.283081

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