GABRQ Antibody, FITC conjugated

Code CSB-PA891564LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GABRQ Polyclonal antibody
Uniprot No.
Target Names
GABRQ
Alternative Names
GABRQ antibody; Gamma-aminobutyric acid receptor subunit theta antibody; GABA(A) receptor subunit theta antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Gamma-aminobutyric acid receptor subunit theta protein (348-611AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Gene References into Functions
  1. We identified truncating mutations in distinct X-linked gamma-aminobutyric acid A (GABAA) receptor subunit-encoding genes, GABRQ and GABRA3.this is the first report of ASD patients with truncating mutations in GABA receptors genes. PMID: 23169495
  2. GABRQ plays important roles in hepatocellular carcinoma development and progression PMID: 22690081
  3. single nucleotide polymorphisms studied in the GABRA4, GABRE, and GABRQ genes are not related to the risk for familial ET. PMID: 21422964
  4. Although GABRQ genes did not show positive association, further studies are necessary to consider the role of other GABA receptor genes in migraine susceptibility PMID: 19087248
Subcellular Location
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein Families
Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRQ sub-subfamily
Database Links

HGNC: 14454

OMIM: 300349

KEGG: hsa:55879

STRING: 9606.ENSP00000359329

UniGene: Hs.283081

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