GCA Antibody

Datasheet
Code CSB-PA009307DSR1HU
Size US$167Purchase it in Cusabio online store
(only available for customers from the US)
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  • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA009307DSR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA009307DSR1HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) GCA Polyclonal antibody
Uniprot No. P28676
Target Names GCA
Alternative Names GCA antibody; GCL antibody; Grancalcin antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Grancalcin protein (1-217AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form Liquid
Tested Applications ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.
Gene References into Functions
  1. Results indicate that heterodimerization of GCA and TLR9 is important for TLR9-mediated downstream signaling and might serve to fine tune processes against viral infection. PMID: 26648480
  2. GCA interacts with SRI in vivo and in vitro. PMID: 12804766
  3. The reported type 1 diabetes association is from a linkage disequilibrium region including three candidate genes, FAP, IFIH1 and GCA. PMID: 18071670
  4. IFIH1 interferon induced helicase, GCA grancalcin or the potassium channel KCNH7 - are potential candidates implicated in the pathogenesis of multiple sclerosis. PMID: 18285833
  5. IFIH1-GCA-KCNH7 locus is not associated with genetic susceptibility to multiple sclerosis in French patients PMID: 19156166

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Subcellular Location Cytoplasm, Cytoplasmic granule membrane, Peripheral membrane protein, Cytoplasmic side
Tissue Specificity Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow.
Database Links

HGNC: 15990

OMIM: 607030

KEGG: hsa:25801

STRING: 9606.ENSP00000394842

UniGene: Hs.377894

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