GCA Antibody

Datasheet

Code	CSB-PA009307DSR1HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA009307DSR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA009307DSR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) GCA Polyclonal antibody

Uniprot No.

P28676

Target Names

GCA

Alternative Names

GCA antibody; GCL antibody; Grancalcin antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Grancalcin protein (1-217AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.

Gene References into Functions

Results indicate that heterodimerization of GCA and TLR9 is important for TLR9-mediated downstream signaling and might serve to fine tune processes against viral infection. PMID: 26648480
GCA interacts with SRI in vivo and in vitro. PMID: 12804766
The reported type 1 diabetes association is from a linkage disequilibrium region including three candidate genes, FAP, IFIH1 and GCA. PMID: 18071670
IFIH1 interferon induced helicase, GCA grancalcin or the potassium channel KCNH7 - are potential candidates implicated in the pathogenesis of multiple sclerosis. PMID: 18285833
IFIH1-GCA-KCNH7 locus is not associated with genetic susceptibility to multiple sclerosis in French patients PMID: 19156166

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Subcellular Location

Cytoplasm. Cytoplasmic granule membrane; Peripheral membrane protein; Cytoplasmic side.

Tissue Specificity

Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow.

Database Links

HGNC: 15990

OMIM: 607030

KEGG: hsa:25801

STRING: 9606.ENSP00000394842

UniGene: Hs.377894

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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