GIMAP4 Antibody

Code CSB-PA009423GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
GIMAP4
Alternative Names
FLJ11110 antibody; GIMA4_HUMAN antibody; Gimap4 antibody; GTPase IMAP family member 4 antibody; GTPase IMAP family member 4 antibody; hIAN1 antibody; HIMAP4 antibody; Human immune associated nucleotide 1 antibody; IAN-1 antibody; IAN1 antibody; IMAP4 antibody; Immunity associated nucleotide 1 protein antibody; Immunity associated protein 4 antibody; Immunity-associated nucleotide 1 protein antibody; Immunity-associated protein 4 antibody; MSTP062 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human GIMAP4
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
During thymocyte development, may play a role in the regulation of apoptosis. GTPase which exhibits a higher affinity for GDP than for GTP.
Gene References into Functions
  1. GIMAP4 regulates secretion of cytokines in early differentiating human CD4(+) T helper lymphocytes and in particular the secretion of interferon-gamma also affecting its downstream targets. PMID: 25287446
  2. Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease PMID: 23041938
  3. molecular and genetic properties; expression in resting T- and B-cells and decreased expression during lymphocyte activation PMID: 11964296
  4. GIMAP1 and GIMAP4 genes are up-regulated by IL-12 and other Th1 differentiation-inducing cytokines in cells induced to differentiate toward Th1 lineage and down-regulated by IL-4 in cells induced to Th2. PMID: 18701445
Subcellular Location
Cytoplasm, cytosol.
Protein Families
TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, AIG1/Toc34/Toc159-like paraseptin GTPase family, IAN subfamily
Tissue Specificity
Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower lev
Database Links

HGNC: 21872

OMIM: 608087

KEGG: hsa:55303

STRING: 9606.ENSP00000255945

UniGene: Hs.647101

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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