GLDC Antibody, HRP conjugated

Datasheet
Code CSB-PA328400LB01HU
Size US$299
Uniprot No. P23378
Protocols ELISA Protocol
Immunogen Recombinant Human Glycine dehydrogenase (decarboxylating), mitochondrial protein (868-984AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (GCSH).
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Glycine dehydrogenase (decarboxylating), mitochondrial (EC 1.4.4.2) (Glycine cleavage system P protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring)), GLDC, GCSP
Immunogen Species Homo sapiens (Human)
Research Area Tags & Cell Markers
Target Names GLDC
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (GCSH).
Involvement in disease Non-ketotic hyperglycinemia (NKH)
Subcellular Location Mitochondrion
Protein Families GcvP family
Database Links

HGNC: 4313

OMIM: 238300

KEGG: hsa:2731

STRING: 9606.ENSP00000370737

UniGene: Hs.584238

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