GMFB Antibody

Code CSB-PA006003
Size US$100
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  • Western Blot analysis of HeLa cells using GMF-β Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
GMFB
Alternative Names
Glia maturation factor beta antibody; GMF antibody; GMF-beta antibody; GMFB antibody; GMFB_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human GMF-β.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells.
Gene References into Functions
  1. GMF-beta is an important player in glioma progression via promoting neovascularization. PMID: 26515590
  2. The distribution of GMF-immunoreactive cells in and around amyloid plaques and neurofibrillary tangles suggests involvement of GMF in inflammatory responses through reactive glia and a role of GMF in Alzheimer disease pathology. PMID: 22035352
  3. GMF co-localizes with amyloid plaques and neurofibrillary tangles in Alzheimer brains, implicating significant upregulation of GMF expression under conditions of neurodegeneration. PMID: 21835226
  4. There is a significant increase in GMF beta protein expression levels in IFN beta-1a treated LX-2 cells. PMID: 18171522
  5. GMFB promoted T-cell differentiation into CD4-/CD8+ cells when analysed by two-colour flow cytometry. PMID: 16115230

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Protein Families
Actin-binding proteins ADF family, GMF subfamily
Database Links

HGNC: 4373

OMIM: 601713

KEGG: hsa:2764

STRING: 9606.ENSP00000350757

UniGene: Hs.151413

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