GNG7 Antibody

Code CSB-PA009619LA01HU
Size US$166
Order now
Image
  • Immunofluorescence staining of MCF-7 cells with CSB-PA009619LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GNG7 Polyclonal antibody
Uniprot No.
Target Names
GNG7
Alternative Names
GNG7 antibody; GNGT7 antibody; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 protein (2-65AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The GNG7 Antibody (Product code: CSB-PA009619LA01HU) is Non-conjugated. For GNG7 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA009619LB01HU GNG7 Antibody, HRP conjugated ELISA
FITC CSB-PA009619LC01HU GNG7 Antibody, FITC conjugated
Biotin CSB-PA009619LD01HU GNG7 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum.
Gene References into Functions
  1. GNG7 is a highly specific promoter methylated gene associated with head and neck cancer. PMID: 23403885
  2. Loss of GNG7 protein expression is a frequent event in head and neck cancer with hypermethylation of the promoter region of GNG7 being probably the mechanism for the observed inactivation. PMID: 22183866
  3. Reduced expression of G-gamma 7 is associated with the histological grade of EHCC and may prove to be a useful marker for predicting the prognosis of human EHCC. PMID: 20543539
  4. GNG7 suppression represents a new prognostic indicator in cases of oesophageal cancer. PMID: 18219292
Subcellular Location
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein Families
G protein gamma family
Tissue Specificity
Expressed in a variety of tissues. Down-regulated in pancreatic and esophageal cancer.
Database Links

HGNC: 4410

OMIM: 604430

KEGG: hsa:2788

STRING: 9606.ENSP00000371594

UniGene: Hs.515544

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*