GNG7 Antibody

Datasheet

Code	CSB-PA009619LA01HU
Size	US$166
	Order now
Image	Immunofluorescence staining of MCF-7 cells with CSB-PA009619LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Promotion
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) GNG7 Polyclonal antibody

Uniprot No.

O60262

Target Names

GNG7

Alternative Names

GNG7 antibody; GNGT7 antibody; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 protein (2-65AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The GNG7 Antibody (Product code: CSB-PA009619LA01HU) is Non-conjugated. For GNG7 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA009619LB01HU	GNG7 Antibody, HRP conjugated	ELISA
FITC	CSB-PA009619LC01HU	GNG7 Antibody, FITC conjugated
Biotin	CSB-PA009619LD01HU	GNG7 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum.

Gene References into Functions

GNG7 is a highly specific promoter methylated gene associated with head and neck cancer. PMID: 23403885
Loss of GNG7 protein expression is a frequent event in head and neck cancer with hypermethylation of the promoter region of GNG7 being probably the mechanism for the observed inactivation. PMID: 22183866
Reduced expression of G-gamma 7 is associated with the histological grade of EHCC and may prove to be a useful marker for predicting the prognosis of human EHCC. PMID: 20543539
GNG7 suppression represents a new prognostic indicator in cases of oesophageal cancer. PMID: 18219292

Subcellular Location

Cell membrane; Lipid-anchor; Cytoplasmic side.

Protein Families

G protein gamma family

Tissue Specificity

Expressed in a variety of tissues. Down-regulated in pancreatic and esophageal cancer.

Database Links

HGNC: 4410

OMIM: 604430

KEGG: hsa:2788

STRING: 9606.ENSP00000371594

UniGene: Hs.515544

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Chemokine signaling pathway PI3K-Akt signaling pathway Ras signaling pathway Apelin signaling pathway Glutamatergic synapse Melanogenesis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：
If CAPTCHA verification fails, click to refresh the CAPTCHA and try again.

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address