GPR114 Antibody

Code CSB-PA008214
Size US$100
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  • Western Blot analysis of COLO205 cells using GPR114 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
ADGRG5
Alternative Names
ADGRG5; GPR114; PGR27; UNQ2524/PRO6017; Adhesion G-protein coupled receptor G5; G-protein coupled receptor 114; G-protein coupled receptor PGR27
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human GPR114.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Adhesion G protein-coupled receptor (GPCR). Transduces intracellular signals through coupling to guanine nucleotide-binding protein G(s) subunit alpha and activation of adenylate cyclase pathway. Isoform 1, but not isoform 2, is constitutively active, as evidenced by elevated basal cAMP levels, and responds to mechanical activation (shaking).
Gene References into Functions
  1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20600896
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Tissue Specificity
Expressed in immune cells. Primarily found in granulocytes. Found in eosinophils.
Database Links

HGNC: 19010

OMIM: 616965

KEGG: hsa:221188

STRING: 9606.ENSP00000290823

UniGene: Hs.187884

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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