GPR12 Antibody, Biotin conjugated

Code CSB-PA009742LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GPR12 Polyclonal antibody
Uniprot No.
Target Names
GPR12
Alternative Names
GPR12; G-protein coupled receptor 12
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human G-protein coupled receptor 12 protein (1-48AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Promotes neurite outgrowth and blocks myelin inhibition in neurons. Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.
Gene References into Functions
  1. Since we have demonstrated that CBD is an inverse agonist for GPR12, this provides novel mechanism of action for CBD, and an initial chemical scaffold upon which highly potent and efficacious agents acting on GPR12 may be developed with the ultimate goal of blocking cancer metastasis. PMID: 28888984
  2. GPR12 may play a role in cell proliferation and survival PMID: 22430950
  3. control of gene expression in vascular endothelial cells in the presence of fluid shear stress and classifies it as a sphingosine 1-phosphate receptor PMID: 12649592
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 1 family
Database Links

HGNC: 4466

OMIM: 600752

KEGG: hsa:2835

STRING: 9606.ENSP00000370844

UniGene: Hs.123034

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