GRAP Antibody, HRP conjugated

Datasheet

Code	CSB-PA618789LB01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) GRAP Polyclonal antibody

Uniprot No.

Q13588

Target Names

GRAP

Alternative Names

Grap antibody; GRAP_HUMAN antibody; GRB2 related adaptor protein antibody; GRB2-related adapter protein antibody; Growth factor receptor bound protein 2 related adaptor protein antibody; MGC64880 antibody; OTTHUMP00000065766 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human GRB2-related adapter protein (1-217AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. Plays a role in the inner ear and in hearing.

Gene References into Functions

Findings suggest that the miR-654-5p/GRAP/Ras/Erk signaling pathway in OSCC cells might contribute to the underlying mechanism through which miR-654-5p participates in the regulation of OSCC progression. PMID: 29364705
Grb2-related adaptor protein (GRAP) was up-regulated in kidney tubules from fibrotic kidneys from diabetic patients, and subsequently confirmed as a novel component of TGF-beta signaling in cultured human renal tubule cells. PMID: 19836472
Results suggest that the GRAP gene might have a role in the pathogenesis of Sjogren's syndrome. PMID: 15174222
Our findings define a pathway involving CD28 binding to Grb-2 and its co-operativity with Vav1 in the regulation of T-cell co-stimulation. PMID: 18295596

Subcellular Location

Membrane; Peripheral membrane protein. Cell junction, synapse.

Protein Families

GRB2/sem-5/DRK family

Database Links

HGNC: 4562

OMIM: 604330

KEGG: hsa:10750

STRING: 9606.ENSP00000284154

UniGene: Hs.567416

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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