GRIK3 Antibody

1. additional experiment showed that the lymph node metastasis tissues had higher GRIK3 expression than their matched primary gastric cancer (GC) tissues. These findings suggested that elevated GRIK3 expression could serve as an independent prognostic biomarker and a novel potential treatment target for patients with GC. PMID: 28631555
2. GRIK3 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
3. 1p34.3 deletion involving GRIK3: Further clinical implication of GRIK family glutamate receptors in the pathogenesis of developmental delay. PMID: 24449200
4. Analyses revealed that polymorphism Ser310Ala of GRIK3 gene is not associated with alcohol dependence or any of its subgroups. PMID: 23006490
5. Our results suggest that the analysed polymorphisms ofANKK1 and ADH4 can play an important part in the pathogenesis of alcohol abuse PMID: 22232963
6. Some support (at a nominal significance level of 0.05/0.01) was found for association between GRIK3 and depression. PMID: 20052609
7. Our study suggests a potential role for GRIK3 for susceptibility to schizophrenia in Indian population. PMID: 19921975
8. Association between the ionotropic glutamate receptor kainate 3 (GRIK3) ser310ala polymorphism and schizophrenia. PMID: 11986986
9. suggestive for a significant role of GRIK3 polymorphism in the pathogenesis of delirium tremens in alcohol-dependent individuals PMID: 16314883
10. These findings do not seem to support the hypothesis of the role of this polymorphism in the pathogenesis of alcoholism. PMID: 16356644
11. significant linkage disequilibrium (LD) indicated by preferential maternal transmission of the GluR7 S310 allele to recurrent major depressive disorder patients (P = 0.012), but not to bipolar I disorder (BPI) patients (P = 1.00) PMID: 16958029
12. The present results, although not robust, support the importance of more extensive investigations of GRIK3, given its potential role in mediating risk for schizophrenia. PMID: 19022628
13. functional GRIK3 Ser310Ala polymorphism is homozygosity is associated with higher scores in harm avoidance and respective subscales of personality traits PMID: 19221446

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HGNC: 4581

OMIM: 138243

KEGG: hsa:2899

STRING: 9606.ENSP00000362183

UniGene: Hs.128848