GSTA2 Antibody

1. the GSTA2 S112T polymorphism is predictive of transplant outcome in patients receiving busulfan in the preparative regimen, at least in association with cyclophosphamide. PMID: 24056816
2. Single nucleotide polymorphism in GSTA2 is associated with low-stage non-small cell lung cancer. PMID: 21792076
3. it is unlikely that glutathione S-transferases GSTA2, GSTM2, GSTO1, GSTO2, and GSTZ1 participate in breast cancer susceptibility. PMID: 19859803
4. studied the five known allelic variants of human glutathione transferase A2-2 (GST A2-2) (EC 2.5.1.18), abundantly expressed in liver and efficiently catalyzing the bioactivation of azathioprine to release 6-mercaptopurine PMID: 20434437
5. The 3D structures of human GSTs A2-2 and A3-3 in complex with Delta(4)-androstene-3-17-dione, were solved. PMID: 20083122
6. Polymorphism identified in the proximal promoter of GSTA2 correlate with its expression in the liver and is expected to be of significance for individual risk of cancer or individual response to chemotherapeutic agents. PMID: 11692074
7. transmutation into an efficient steroid isomerase PMID: 12023294
8. no association was observed between individual GSTA2 polymorphisms and haplotypes and individual susceptibility to breast cancer. PMID: 19639209
9. Overexpression of GSTA2 by transient transfection protected Colo 320HSR cells against both cycle arrest and apoptosis following exposure to HN2. PMID: 15778998

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HGNC: 4627

OMIM: 138360

KEGG: hsa:2939

STRING: 9606.ENSP00000420168

UniGene: Hs.94107