GSTZ1 Antibody

1. Some properties of cytosolic and mitochondrial GSTZ1 differed. PMID: 29853471
2. mild hypersuccinylacetonaemia (MHSA)can be caused by sequence variants in GSTZ1. Such individuals have thus far remained asymptomatic despite receiving no specific treatment. PMID: 27876694
3. rs7975 GG carriers had an increased risk of below-reference sperm motility PMID: 26970898
4. We conclude that the lower expression of GSTZ1 in Whites who possess the K carrier haplotype results in lower enzymatic activity and slower metabolism of DCA, compared with those who possess the non-K carrier haplotype PMID: 25738370
5. Haplotype variations in glutathione transferase zeta 1 influence the kinetics and dynamics of chronic dichloroacetate in children PMID: 25079374
6. The data indicates no association between GSTZ1 genotypes and risk of gastric cancer. PMID: 24719983
7. Two SNPs, rs282070 located in intron 1 of the MAP3K7 gene, and rs2111699 located in intron 1 of the GSTZ1 gene, were significantly associated (after adjustment for multiple testing) with longevity in stage 2 PMID: 22576335
8. The ping-pong catalytic mechanism of Se-hGSTZ1-1 is similar to that of the natural GPX. PMID: 23280616
9. Elucidation of the role of individual residues in the N-terminal, SSC motif of human GSTZ1. PMID: 23299908
10. This study was performed on 228 BPD patients and 234 control subjects. Among early-onset patients, the variant alleles of Glu32Lys and G-1002A increased BPD susceptibility. PMID: 22374552
11. e report for the first time the conversion of human glutathione transferase Zeta (hGSTZ1-1) into seleno-hGSTZ1-1 by means of genetic engineering in eukaryotes. PMID: 22561244
12. The present results indicate that the haplotype of "-1002A, 32Lys, 42Arg" (containing three variant alleles) of GSTZ1 have protective effect compared to the other haplotypes. PMID: 22729907
13. Our study did not support any association between susceptibility to exudative AMD (age-related macular degeneration) and polymorphisms of GSTZ1. PMID: 21948024
14. Data suggest neonatal onset and age-related increase in GSTZ1 protein expression during liver development/growth. GSTZ1 haplotype influences activity with dichloroacetate but not protein expression. PMID: 22028318
15. polymorphisms of GSTZ1 showed strong linkage disequilibrium among cancer patients and control su PMID: 21823988
16. Results describe the genotypic frequencies of glutathione S-transferase Z1 polymorphisms among an Iranian population. PMID: 21107728
17. The results of this study did not support the association between genetic polymorphisms of glutathione S-transferase Z1 (GSTZ1) and susceptibility to schizophrenia. PMID: 21183226
18. subjects with polymorphisms in GSTZ1 have a higher trihalomethanes induced bladder cancer susceptibility PMID: 20675267
19. A new allele of GSTZ1 (maleylacetoacetate isomerase), characterized by a Thr82Met substitution and termed GSTZ1d, has been identified by analysis of the expressed sequence tag (EST) database. PMID: 11692075
20. Single nucleotide polymorphisms may alter GSTZ1 expression, which may alter the pharmacokinetics of DCA, which is used therapeutically for the treatment of lactic acidosis. PMID: 16609361
21. Kinetic studies revealed that the catalytic mechanism of Se-hGSTZ1-1 belong in a ping-pong mechanism similar to that of the natural glutathione peroxidase. PMID: 18373941
22. The results are consistent with the hypothesis that reduced dopamine metabolism adversely affects cognition. PMID: 18628685

Show More

Hide All

HGNC: 4643

OMIM: 603758

KEGG: hsa:2954

STRING: 9606.ENSP00000216465

UniGene: Hs.655292