H3F3C Antibody

Datasheet

Code	CSB-PA276067
Size	US$166
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Image	Gel: 12%SDS-PAGE, Lysate: 20 μg, Lane 1-2: Human fetal brain tissue, Hela cells, Primary antibody: CSB-PA276067(H3F3C Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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Product Details
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Target Background

Product Details

Uniprot No.

Q6NXT2

Target Names

H3F3C

Alternative Names

H3 histone, family 3C antibody; H3.5 antibody; H3C_HUMAN antibody; h3f3c antibody; Histone H3.3C antibody; Histone H3.5 antibody; Histone variant H3.5 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein of Human H3F3C

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
WB	1:200-1:1000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Hominid-specific H3.5/H3F3C preferentially colocalizes with euchromatin, and it is associated with actively transcribed genes.

Gene References into Functions

H3.5 may play roles in DNA synthesis, but not apoptosis, and its expression is regulated by gonadotropins PMID: 29179259
H3.5 preferentially colocalizes with euchromatin, and it is associated with actively transcribed genes and can replace an essential function of RNAi-depleted H3.3 in cell growth. PMID: 21274551

Subcellular Location

Nucleus. Chromosome.

Protein Families

Histone H3 family

Tissue Specificity

Specifically expressed in the seminiferous tubules of testis.

Database Links

HGNC: 33164

OMIM: 616134

KEGG: hsa:440093

STRING: 9606.ENSP00000339835

UniGene: Hs.448697

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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