HERC3 Antibody

Datasheet

Code	CSB-PA618972LA01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) HERC3 Polyclonal antibody

Uniprot No.

Q15034

Target Names

HERC3

Alternative Names

HERC3 antibody; KIAA0032Probable E3 ubiquitin-protein ligase HERC3 antibody; EC 2.3.2.26 antibody; HECT domain and RCC1-like domain-containing protein 3 antibody; HECT-type E3 ubiquitin transferase HERC3 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Probable E3 ubiquitin-protein ligase HERC3 protein (1-200AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The HERC3 Antibody (Product code: CSB-PA618972LA01HU) is Non-conjugated. For HERC3 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA618972LB01HU	HERC3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA618972LC01HU	HERC3 Antibody, FITC conjugated
Biotin	CSB-PA618972LD01HU	HERC3 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Gene References into Functions

HERC3 negatively regulates NF-kappaB signaling by enhancing RelA subunit degradation. PMID: 26476452
we found somatic mutations of HERC2, HERC3, TRIP12, UBE2Q1 and UBE4B genes in gastric carcinoma and colorectal carcinomas with microsatellite instability PMID: 22124266

Subcellular Location

Cytoplasm. Cytoplasmic vesicle. Note=Also found in vesicular-like structures.

Database Links

HGNC: 4876

OMIM: 605200

KEGG: hsa:8916

STRING: 9606.ENSP00000264345

UniGene: Hs.35804

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Ubiquitin mediated proteolysis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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